11 results
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
Aortic Dissection ... Examine for: • Pulse ... deficit/differential ... Dissection #diagnosis #management ... #vascular
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... proteolysis: Severe aortic ... Syndrome #Diagnosis #Management ... #treatment #hematology ... #differential
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... - Aortic mural ... pathophysiology #hematology ... #differential # ... diagnosis #vascular
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... abnormalities • Muscular ... Disease #diagnosis #management ... #treatment #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Cathepsin G release → vascular ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... and bullous or vesicular ... < 30 years - Aorta ... diminished, or tender pulses ... #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Ischemic optic ... Rheumatic fever • Aortic ... Diminished peripheral pulses ... #joint #pain #differential ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
< 30 years • Aorta ... claudication, pulse ... deficits vascular ... Arteritis): • Aorta ... #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
and diplopia) • Vascular ... Behcet disease) Differential ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... very remarkable w/differential ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management