16 results
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework ... of Leg Pain: ... Limb ischemia • Aortic ... refill - Poor pulses ... #diagnosis #lower
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... syndrome - SLE Neurologic ... Rheumatic fever • Aortic ... Diminished peripheral pulses ... #differential #diagnosis
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
and Pathophysiology ... less compliant arteries ... disorders: - Aortic ... regurgitation - Aortic ... #Pathophysiology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... ) -> Leg Ulcers, ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
Takayasu’s Arteritis ... , CRP, WBC - Aortic ... - Arm/Leg Claudication ... Decr palpable pulses ... #Vasculitis #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
< 30 years • Aorta ... arthralgia, arm/leg ... claudication, pulse ... ): • Aorta and ... tract, and often causes
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Manifestations • Optic ... Scotoma, Ocular pain ... involvement: Intractable nausea ... Manifestations #diagnosis ... #neurology #symptoms
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
of the Hip • Arthritis ... Chondrodysplasia Neurologic ... Sacroiliac Joint Pain ... #causes #symptoms ... #signs #diagnosis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... those coming off aorta ... claudication: pain ... chews, not just pain ... required +/- prompt ophthalmology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... < 30 years - Aorta ... diminished, or tender pulses ... , testes -> pain