29 results
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Basophilic stippling, Bite ... cell, Elliptocyte
Alpha-gal Syndrome (AGS) - Diagnosis Algorithm
Does patient have recurrent episodes of urticaria, angioedema or isolated GI
AGS) - Diagnosis Algorithm ... - Known tick bites ... irritation at site ... of tick bite • ... AGS #Diagnosis #Algorithm
Morphologic Findings in Red Blood Cells
Basophilic stippling - Small blue dots in red cells, due to
Heinz bodies (Bite ... Bite cells: sharp ... bite-like defects ... cell membrane Elliptocytes
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... pyropoikilocytes, elliptocytes ... Differential #Diagnosis #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Differential Diagnosis Algorithm ... disease US — Normal Bile ... US - Dilated Bile ... Ducts • Common Bile ... Differential #Diagnosis #Algorithm
Irritable Bowel Syndrome (IBS) Treatment Algorithm

IBS-Constipation:
 • Constipation: Osmotic laxatives
 • Abdominal pain: Antispasmodics

IBS-Diarrhea:
 • Diarrhea:
IBS) Treatment Algorithm ... Diarrhea: Loperamide, Bile ... Treatment #Management #Algorithm
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 
1. Old samples
#Schistocytes #Pyknocytes ... #Elliptocytes # ... Echinocytes #BurrCells #Bite
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Bite Cell RBC: G6PD ... Oxidative drugs Elliptocyte
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Differential Diagnosis Algorithm ... further History • Bite ... Differential #Diagnosis #Algorithm
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Differential Diagnosis Algorithm ... • US - Normal Bile ... • US - Dilated Bile ... Transaminitis #Algorithm