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diagnosis hematology differential management causes oncology anemia workup microscopy clinical cll elevatedmcv hepatitis injury leukemia liver lymphocytic macrocytosis polycythemia syndrome
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... on Smear • Chronic ... • Anemia of Chronic ... Spherocytes on Smear ... #Causes #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Differential Diagnosis Algorithm ... Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Differential Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Spherocytes, RBC ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
expression of Kell RBC ... associated with chronic ... McLeod #Syndrome #Smear ... #Pathology #Microscopy
Plasmodium - Identification Algorithm • P. falciparum: RINGS AND GAMETOCYTES PREDOMINATE, Small delicate rings, <1/3 size
Identification Algorithm ... rings, <1/3 size RBC ... Multiple rings/RBC ... Identification #Algorithm ... #pathology #smear
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Artifact (redo CBC ... : • Acute or Chronic ... effect following treatment ... #Causes #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
and Management Algorithm ... Initial labs: CBC ... Reticulocytes, smear ... MAHA likely: • Smear ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... Normal Blood Smear ... Neutrophils - Low RBC ... Pernicious Anemia RBCs ... #Causes #Hematology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
anorexia, ARDS ​• RBC ... phase: Peripheral smear ... coccobacillus within the RBCs ... ​• Chronic phase ... TREATMENT: ​• Acute
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Differential Diagnosis Algorithm ... Initial Workup: CBC ... acid, peripheral smear ... Differential #Diagnosis #Algorithm ... #hematology #workup
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