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management differential hematology algorithm liver blood lfts product shock transaminitis transfusion aclf activation acute aih alcoholic amiodarone anemia aplastic autoimmune
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Drug-Induced Liver Injury ... (DILI) Viral Hepatitis ... #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... evidence of liver failure ... • Infections: Hepatitis ... #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... • Autoimmune hepatitis ... #Diagnosis #Algorithm ... #hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... with severe liver injury ... or acute liver failure ... #HepatitisB ... Indications #management #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... to acute liver failure ... pattern of liver injury ... regarding need for treatment ... #Management #Hepatology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Supportive with treatment ... to acute liver failure ... Hepatobiliary #hepatology ... #hepatitis #differential ... #diagnosis
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
- Differential Diagnosis ... Insufficiency, Liver Failure ... Medications, Spinal Cord Injury ... #criticalcare # ... algorithm #treatment
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... : 33% • Treatment ... CVP, left heart failure ... : No • Treatment ... #hematology #diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... Identify Acute Liver Failure ... liver #chemistry #diagnosis ... #differential #Hepatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... hypoTN, renal failure ... Related Acute Lung Injury ... #Transfusion #diagnosis ... #management #hematology
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