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Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Causes of Acute Liver ... Injury #Diagnosis ... #Hepatology #Acute ... #Liver #Injury ... Incidence #Table #Failure
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... months without treatment ... Injury (DILI) ... #Hepatology #gastroenterology ... #management #diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... : Liver Injury ... failure 1) Hepatocellular ... Diagnosis: • ... #Diagnosis #hepatology
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
- Differential Diagnosis ... Traumatic brain injury ... Hyperglycemia, Hyponatremia ... Hypoxia, Uremia, Liver ... failure, Eclampsia
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
- Differential Diagnosis ... Insufficiency, Liver ... Failure, Toxins ... Medications, Spinal Cord Injury ... #criticalcare #
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis ... non-essential drug/HDS treatments ... #Injury #Diagnosis ... #Algorithm #hepatology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Supportive with treatment ... failure • Supportive ... Liver transplant ... Hepatobiliary #hepatology ... #differential #diagnosis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Failure (ALF): ... • Liver injury ... hepatocellular injury ... #chemistry #diagnosis ... #differential #Hepatology
Shock Classification and Differential Diagnosis
SHOCK
 • MAP <65, SBP <90, drop in SBP > 40
 •
and Differential Diagnosis ... Insufficiency, Liver ... Failure, Toxins ... Medications, Spinal Cord Injury ... #Types #criticalcare
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
infection with severe liver ... injury (INR > 2 ... mg/dL) or acute liver ... failure #HepatitisB ... Indications #management #hepatology