45 results
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... #Syndromes #diagnosis ... #pathophysiology ... #signs #symptoms
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
of acute liver failure ... Subclinical myocardial injury ... : Acute lung injury ... #Signs #Symptoms ... #Diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... , Compartment syndrome ... , Electrical injury ... Dermatomyositis) AKI - Pathophysiology ... Treatment: 1
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
- Differential Diagnosis ... Insufficiency, Liver Failure ... Medications, Spinal Cord Injury ... Abdominal compartment syndrome ... #criticalcare #
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... #rheumatology
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
Classification Types - Pathophysiology ... leading to organ failure ... #Shock #Types #Pathophysiology ... #Comparison #criticalcare ... #diagnosis #classification
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... Bradycardia R - Renal failure ... • Aggressive treatment ... #diagnosis #management ... #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Treatment: • ... #management #hematology