17 results
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
- Diagnosis Diagnostic ... Abnormal pathergy test ... medium-large joints) • Vascular ... and peripheral vascular ... #criteria #rheumatology
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Echocardiogram, Vascular ... imaging → Test ... Hypercoagulable #Workup #hematology ... #diagnosis #algorithm ... #hematology #VTE
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Liver Function Tests ... Algorithm #Causes #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
underlying disease (eg ... • Infection (eg ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
and diplopia) • Vascular ... Positive pathergy test ... is a skin prick test ... ) Differential Diagnosis ... signs #symptoms #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... improves quickly with rest ... osteopetrosis, avascular ... Joint #Pain #MSK #rheumatology ... #differential #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... Prednisone 5mg/kg ... Differentiation #Syndrome ... #management #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Vascular Sludging ... Labs/Diagnosis: ... tissue disorder (e.g ... Cryoglobulins #diagnosis ... classification #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
antiinflammatory properties e.g ... blockers had the best ... #Rheumatology # ... diagnosis #management ... #Dermatology
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
: • Nephrotic syndrome ... AL Cardiac: • LVH ... , low-voltage EKG ... Carpal tunnel syndrome ... activity of factor X, vascular