30 results
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis Table ... Toxin-Mediated HUS ... HUS (aHUS) ... #TMA #hematology ... diagnosis #HUS
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
- TTP VS HUS ... Often hard to differentiate ... HemolyticUremicSyndrome #HUS ... Comparison #Diagnosis #Table ... #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolytic-uremic syndrome (ST-HUS ... known as atypical HUS ... Drug-induced thrombotic microangiopathy ... #diagnosis #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
TMA: Thrombotic microangiopathy ... HUS), Serum creatinine ... HUS) Treatment ... #treatment #rheumatology ... #hematology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically Relevant HES ... suspect underlying hematologic ... Hypereosinophilic #Syndrome #HES ... #Hematology #eosinophilia ... eosinophils #diagnosis #management
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
to Thrombotic Microangiopathy ... (TMA) - Differential ... Diagnosis and Management ... #TMA #Differential ... #Algorithm #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... Consumption: - Microangiopathy ... : DIC, TTP, HUS ... Thrombocytopenia #Differential ... Diagnosis #Framework #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Schistocytes: Microangiopathic ... DIC, TTP, HUS) ... Smear #Analysis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Mechanical Trauma (Microangiopathic ... - Thrombotic microangiopathy ... uremic syndrome (HUS ... Extravascular #Causes #differential ... #diagnosis #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... TTP (atypical HUS ... ), Shiga-toxin HUS ... #TMAs #hematology ... diagnosis #ttp #hus