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diagnosis hematology hemolysis hemolytic oncology workup agglutinin algorithm ana antibody antinuclear arteritis classification cold cytoplasmic disease disorders dyspnea extravascular fat
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Dyspnea - Differential ... failure - CAD/ACS ... Transverse myelitis • Hematology ... : - Anemia • ... #dyspnea #sob #differential
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... HUS, DIC, HELLP, AS ... #Differential # ... classification #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Intravascular Hemolysis - Differential ... Cold AIHA • PCH ... immune-complex hemolytic anemia ... #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Grafts, Valves, AS ... Drug-associated, PCH ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... Platelet #Disorders #Differential ... #Workup #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Scl70 (in some cases ... /SjS OS - AMA ... body-like: - Neurologic ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... younger pts) Differential ... Disorders Such As ... #hematology #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... Haptoglobin - Low as ... immune hemolytic anemia ... WBC count and differential ... Diagnosis #Workup #Hematology
FAT RBC Mnemonic for Causes of Macrocytic Anemia (MCV > 100) F - Folate (Fetus) and B12 Deficiency
RBC Mnemonic for Causes ... released from marrow as ... FATRBC #Mnemonic #Causes ... #Differential # ... Diagnosis #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... blood count with differential ... Syndromes #diagnosis #hematology
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