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diagnosis hematology workup algorithm anemia hemolytic oncology polycythemia agglutinin aids ana antibody antinuclear autoimmune behcet biliary bone cholangitis cirrhosis classification
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
- Polycythemia Differential ... Polycythemia - Acquired Causes ... Cardiac/pulmonary disease ... Polycythemia #Vera #PV #Differential ... Diagnosis #Algorithm #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... disease progresses ... bile ducts Differential ... , IgG4 related disease ... diagnosis #workup #hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Grafts, Valves, AS ... Drug-associated, PCH ... , Drugs, Liver Disease ... #Diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... HUS, DIC, HELLP, AS ... Hemolytic #Anemia #Differential ... classification #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... PT, aPTT(liver disease ... (CVID, WAS), (neurologic ... bypass), LFT (liver disease ... #Workup #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Hematogenous spread as ... #differential # ... #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Scl70 (in some cases ... /SjS OS - AMA ... body-like: - Neurologic ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... younger pts) Differential ... Disorders Such As ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... : Arterial (MCC-small ... ) Differential Diagnosis ... Reactive Arthritis, AS ... signs #symptoms #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
in HIV / AIDS - Differential ... Demyelinating disease ... caused by the JC ... • Symptoms: AMS ... CNS #Infections #differential
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