19 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
tubule of the kidney ... Most cases diagnosed ... • recurrent fractures ... : - Renal failure ... Hyophosphatasia #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Intestine - Other causes ... Intestine • Kidney ... Pregnancy - Renal ... #Algorithm #hepatology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Syndrome (HRS) - Diagnostic ... haematuria, Normal renal ... ultrasound HRS-NAKI ... - No other cause ... HRSAKI #HRSNAKI #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... Infection exposure (l MD ... not required in all ... #Differential #Diagnosis ... #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Not all MAHAs are ... TMAs cause MAHA ... /o significant renal ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Polycythemia Differential Diagnosis ... Polycythemia - Acquired Causes ... Hypoxia-independent: Post-renal ... Matthew Ho, MD ... #Algorithm #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Heart, lung, and kidney ... tests ↑ AST ↑ ALT ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Caused by splanchnic ... ultrasound ... Exclude other AKI causes ... evaluation essential in all ... Hepatorenal #Syndrome #Hepatology
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 • Severe protein malnutrition after bariatric surgery
 • More
Gastric bypass causes ... oxalate in the kidney ... and forms renal ... Gastroenterology and Hepatology ... gastroenterology #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... involve one, two, or all ... characteristic feature ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology