8 results
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
retroperitoneal masses ... of pampiniform plexus ... and scrotal vein plexus ... #Varicocele #Pathophysiology ... Symptoms #Urology #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • recurrent fractures ... collection with EDTA Pathophysiology ... : - Renal failure ... Hyophosphatasia #hepatology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Syndrome (HRS) - Diagnostic ... haematuria, Normal renal ... ultrasound HRS-NAKI ... - No other cause ... HRSAKI #HRSNAKI #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... Antithrombin Ill • Ultrasound ... ) Differential Diagnosis ... Liver #Pregnancy #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Bleeding (64%) • Renal ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Caused by splanchnic ... perfusion + ↑ renal ... Pathophysiology: ... Normal kidney ultrasound ... Hepatorenal #Syndrome #Hepatology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
-> Pathologic fractures ... Renal • Incr ... resorption, Incr renal ... PagetsDisease #pathophysiology ... #diagnosis #signs
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
anemia (MAHA) Pathophysiology ... Biopsy to confirm diagnosis ... • Refractory cases ... → consider PLEX ... rheumatology #nephrology #diagnosis