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management hemeonc acromegaly apml cell chronic cll compartment dermatology differentiation emergencies endocrinology hemophagocytic hepatology hepatorenal hlh hrs leukemia leukostasis lymphocytic
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... #management #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... , breast CA - Hematologic ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... ): - Hematologic ... : - Facial swelling ... #HemeOnc #Diagnosis
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
(SPS) - Diagnosis ... Pathophysiology ... antibody that works ... Treatment: • ... #Management #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
size, coarsening facial ... Beckwith Wiedemann syndrome ... and Workup: • ... Endocrinology #Treatment ... #Pathophysiology
Compartment Syndrome Pearls A vicious cycle of increased pressure within a facial compartment leading to compression of
Compartment Syndrome ... pressure within a facial ... Pathophysiology: ... onset of ischemia Treatment ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... Presentation • Common Signs ... Pathophysiology ... Treatment Approach ... #Management #Hematology
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