15 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Prunelle Getten #AdultOnset ... Disease #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Must rule out other ... BrighamChiefs #AdultOnset ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... glucocorticoid treatment ... signs or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Syndrome #Diagnosis #Management ... #treatment #hematology ... #differential
REBEL Review 79: Treatment of Hemophilia 

Walkina Out of Pt Room, You Should Know... 
1. Type
REBEL Review 79: Treatment ... Hemophilia Walkina Out ... Required Weight (kg ... #hemophilia #hematology ... #management #treatment
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
with response to treatment ... Glucocorticoids (0.6 mg/kg ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Gout - Management
Acute Gout Flare
 1) colchicine, NSAIDs, glucocorticoids
 2) Anakinra (IL-1 inhibitor)
When to Start Urate
Gout - Management ... Acute Gout Flare ... presence of tophi 2) radiologic ... #Management #treatment ... #rheumatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... amphetamines) Toxic: • Radiologic ... #Hyperthermia #Differential ... Checklist #Diagnosis #Management ... #Workup
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Prednisone 5mg/kg ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management