14 results
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... Deficiency • MDS ... #diagnosis #algorithm ... #hematology #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential Diagnosis ... Non-hemolytic: ACD, Aplastic ... Infections Macrocytic ... Reticulocytosis, MDS ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... (MDS) (normal or ... #hematology #diagnosis ... #management
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5. ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Can progress to MDS ... #Anemia #diagnosis ... #management #treatment ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... (MD) - Diagnosis ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... #MDS #Diagnosis
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5 ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Matthew Ho, MD
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... • Aplastic Anemia ... Workup: • Complete ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... (MAS) Classified ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology