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management differential workup antibodies classification disease myositis treatment vasculitis 1: activation algorithm ana anemia antinuclear antiphospholipid aplastic apls apml autoimmune
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
manifestations +++ 2. ... dermatomyositis, SLE ... #differential #diagnosis ... #dermatology #oncology ... #clinical #skin
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
TIF1y, NXP2, Mi-2, ... SAE Anti-Synthetase ... Syndrome: Jo-1, ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
anti-synthetase syndrome ... at diagnosis). ... Can also see mechanics ... weakness after 2 ... #rheumatology
Susac Syndrome - Clinical Triad - Central nervous system dysfunction - Branch retinal artery occlusion -
Susac Syndrome - ... Clinical Triad ... antiplatelet 2. ... #Diagnosis #Management ... #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... common in APL (2- ... Moderate > 2/3 and ... #management #hematology ... #oncology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Damage Through 2 ... : • Clinical triad ... Labs/Diagnosis: ... erythematosus (SLE ... classification #rheumatology
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
- Diagnosis Diagnostic ... oral ulcers with 2 ... AND • Meeting ≥ 2 ... test Most Common Clinical ... #criteria #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... erythematosus [SLE ... Increased soluble IL-2 ... #Diagnosis #Management ... #Hematology #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Orange or Hep C Clinical ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
microscopy and serial ... likely it will be clinically ... ), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
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