2930 results
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
Causes of Hyperkalemia ... Hyperkalemia is caused ... by excess potassium ... intake, impaired potassium ... rarely the sole cause
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
review of the Renin-Angiotensin-Aldosterone ... with excreting potassium ... sodium, which causes ... inhibiting drug classes ... #Pharmacology #Renin
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... suggests extra-renal causes ... tumor - ↓ Renin ... #differential #potassium
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Decreased renal potassium ... Drugs Increased potassium ... (oral/iv) • Potassium-rich ... Diabetic Nephropathy Renin ... Normal, Renin High
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... renovascular HT, Renin-secreting ... diagnosis #algorithm #causes ... #nephrology #potassium
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... ARBs Decreased Renin ... Pharmacology #Impaired #Potassium
Causes of Hyperkalemia - Differential Diagnosis Algorithm
 • Increased Intake
 • Reduced Excretion (IV potassium with
Causes of Hyperkalemia ... Excretion (IV potassium ... Diagnosis #Algorithm #Causes
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Renovascular HTN, Renin ... Diagnosis #Algorithm #causes ... #potassium #low
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Hyperkalemia • Direct renin ... Aliskiren) • Renin ... #pharmacology #potassium
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... blood volume • ↑ Renin ... artery stenosis, Renin ... secreting tumor • ↓ Renin ... hypokalemia #urine #potassium