15 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... allergy, drug reaction ... glucocorticoid treatment ... Disorders #Algorithm #Differential ... #diagnosis #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... without other cause ... : 33% • Treatment ... , and CXR with pulmonary ... #hematology #diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... fraction < 20% Differential ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Edema in 70% of cases ... Resolution > 15 days Differentials ... disease: symptomatic treatment ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... Diagnosis Neonate ... hypertension and/or drug treatment ... #diagnosis #causes ... #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... #Transfusion #diagnosis ... #management #hematology
Differential diagnosis
The table summarizes the most common diseases, that present with consolidation.
Chronic diseases are indicated in
Differential diagnosis ... lobar pneumonia caused ... respond to the treatment ... #Diagnosis #Radiology ... #Pulmonary #CXR
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... initiation • Differential ... Renal Failure Treatment ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... #Transfusions #diagnosis ... #management #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Diagnosis Framework ... tract, and often causes ... mucositis - Rash ... disease, drug reactions ... #diagnosis #rheumatology