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diagnosis hematology differential hemolytic signs symptoms disease rheumatology sle complications erythematosus mimickers systemic activation agglutinin aiha anorexianervosa autoantibodies autoimmune bandemia
Pathophysiology, Signs and Symptoms of Hemolytic Anemia #Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, ... Symptoms of Hemolytic Anemia ... #Pathophysiology ... #Hemolytic #Anemia ... #hematology #diagnosis
Hemolytic anemia in Wilson's disease #Wilsons #Disease #hemolytic #anemia #Hematology #pathophysiology
Hemolytic anemia ... Disease #hemolytic #anemia ... #Hematology #pathophysiology
Pathophysiology of Hemolytic Anemia - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects) -
Pathophysiology ... of Hemolytic Anemia ... environment #Pathophysiology ... #Hemolytic #Anemia ... #hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic Anemia ... (AIHA) Pathophysiology ... Autoimmune #Hemolytic #Anemia ... #Pathophysiology ... #diagnosis #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Photosensitivity 29% - Raynaud's ... - Hemolytic anemia ... Diagnosis and Lupus ... : Drug-induced lupus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... defect (rare) Raynaud's ... ) Blood (75%): Anemia ... Thrombocytopenia #Lupus
Great Mimickers - SHALLOTS Mnemonic S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
dermatitis, dementia, anemia ... anything L - Lupus ... arthritis, alopecia, Raynaud ... Could be lupus in
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Reticularis, Vasculitis, Raynaud's ... Phenomenon #Lupus ... Manifestations #pathophysiology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Diseases: • Systemic lupus ... Differential #Diagnosis #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology ... #anemia
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