1457 results
Nephron Reabsorption Sites
 • Proximal Convoluted Tubule
 • Proximal Straight Tubule
 • Thick Ascending Limb
 •
Nephron Reabsorption ... Bladder #Nephron #Reabsorption ... pathophysiology #nephrology
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext

#Pathophysiology #Mechanism #Nephrology
block glucose reabsorption ... Pathophysiology #Mechanism #Nephrology ... SLGT2 #Inhibitors #Reabsorption
Proximal Renal Tubular Acidosis (RTA) Ttype 2 Overview

HCO3 reabsorptive failure
Lowering of threshold for HCO3 absorption in
Overview HCO3 reabsorptive ... threshold for HCO3 absorption ... Diagnosis #Management #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
↑ Renin ↑ Ca++ reabsorption ... Hypocalciuria ↓ Mg++ reabsorption ... Pathophysiology #nephrology
Hyperkalemic Distal Renal Tubular Acidosis (RTA) Type 4 - 

Failure to acidify urine in collecting duct
to reduced Na reabsorption ... Diagnosis #Management #Nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
→ ADH → water reabsorption ... Pathophysiology #diagnosis #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
resistance • ↑ Na+ reabsorption ... pathophysiology #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
• Inhibit Na+ reabsorption ... effect on sodium reabsorption ... mediated water reabsorption ... #Pharmacology #nephrology
Pathophysiology of The Nephron - Electrolyte and Water Exchange

The nephron — electrolyte and water exchange. 
180
Pathophysiology #Nephrology ... #Electrolytes #Reabsorption
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
a renal tubule reabsorptive ... (defective Na reabsorption ... (defective Na reabsorption ... Diagnosis #Causes #nephrology