1101 results
diagnosis management symptoms signs differential pharmacology treatment algorithm cardiology syndrome nephrology endocrinology clinical hematology causes infectiousdiseases msk infections pulmonary complications
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
- Positive: CD2 ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... Rarely can be CD4
How dendritic cells (DCs) orchestrate adaptive immunity 1- Sensing of microbial and damage signals by DCs 2- Phenotypic
changes during DCs activation ... 3- DC are professional ... immunity #immunology #pathophysiology
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
Viruses: HSV (reactivation ... Viruses: HSV (reactivation ... Viruses: CMV (reactivation ... ), VZV (reactivation ... ), CMV (reactivation
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Complement Pathway Activation ... Vasculitis #HUV #Pathophysiology
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
anaphylaxis is mast cell activation ... Inappropriate mast cell activation ... cells • ANS activation ... #Anaphylaxis #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
with host -> Activation ... auto-reactive B and CD ... RheumaticFever #pathophysiology
Inflammatory mechanism of asthma. Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
cells exposed to activation ... dendritic cell (DC ... activate naive CD4 ... #asthma #pathophysiology
Autoimmune Gastritis - Pathophysiology Anti-ParietaI Cell, CD4+ T Cells, Autoantibodies -> x Parietal Cells, x HCL, x
Autoimmune Gastritis - Pathophysiology ... Anti-ParietaI Cell, CD4 ... Autoimmune #Gastritis #Pathophysiology
Non-Infective Endocarditis - Pathophysiology Non-infective Endocarditis Pathophysiology: • Valves usually undamaged - Etiology poorly understood but thought
Endocarditis - Pathophysiology ... Non-infective Endocarditis Pathophysiology ... Infective Endocarditis Pathophysiology ... forms and promotes activation ... NBTE #Marantic #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
because T-Cell activation ... -> Particular CD4 ... Allergy #Immunology #pathophysiology
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