3458 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... • Endogenous reactivation ... Inhibitor: • Risk of reactivation ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... • Endogenous reactivation ... Inhibitor: • Risk of reactivation ... TB #Diagnosis #Management
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Viruses: HSV (reactivation ... Viruses: HSV (reactivation ... Viruses: CMV (reactivation ... ), VZV (reactivation ... ), CMV (reactivation
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Complement Pathway Activation ... Vasculitis #HUV #Pathophysiology
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
anaphylaxis is mast cell activation ... Inappropriate mast cell activation ... cells • ANS activation ... #Anaphylaxis #pathophysiology
Non-Infective Endocarditis - Pathophysiology
Non-infective Endocarditis Pathophysiology:
 • Valves usually undamaged - Etiology poorly understood but thought
Endocarditis - Pathophysiology ... Non-infective Endocarditis Pathophysiology ... Infective Endocarditis Pathophysiology ... forms and promotes activation ... NBTE #Marantic #pathophysiology
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
fibrin → preventing activation ... Tranexamic #Acid #pathophysiology
Pathophysiological mechanisms of diastolic heart failure HFpEF and possible therapeutic interventions.
Hypertension → Overload
Diabetes → Oxidative stress,
Oxidative stress, RAGE activation ... #dchf #hfpef #pathophysiology
Alcohol Withdrawal Summary

Pathophysiology, Symptoms, Cause, Course, Management 

#Diagnosis #Management #Pathophysiology #Alcohol #Withdrawal #Symptoms
Withdrawal Summary Pathophysiology ... Cause, Course, Management ... #Diagnosis #Management ... #Pathophysiology
Toxic alcohols - Methanol and Ethanol - Pathophysiology + Management Algorithm

By Loran Hatch, DO

#Toxic #alcohols #Methanol
and Ethanol - Pathophysiology ... + Management Algorithm ... Methanol #Ethanol #Pathophysiology ... #Management #Algorithm