14 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Antibiotics Class Overview ... Rapidly cidal drug ... gram negative activity ... skin/soft tissue infections ... cidal nature) #Pharmacology
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
Antibiotics Class Overview ... positive agent with activity ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... drug use • Silicosis ... involvement - seeding ... Tuberculosis Treatment ... Initiating Treatment
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antibiotics Class Overview ... vs Candida -> Drug ... severe Candida infections ... Echinocandins lack activity ... Anidulafungin #Pharmacology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... drug use • Silicosis ... involvement - seeding ... Tuberculosis Treatment ... Initiating Treatment
Diagnosis and Management of Achalasia - ACG Guidelines

Who to suspect?
 • Patients presenting with progressive dysphagia
classic "bird beaking ... POEM Symptomatic Treatment ... Botulinum toxin • Pharmacologic ... ACG #Guidelines #gastroenterology ... #Treatemtn
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
and spectrum of activity ... Antibiotics are drugs ... treat bacterial infections ... Imagine treatments ... #Antibiotics #pharmacology
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Antibiotics Class Overview ... other agents are: activity ... including PCP PNA (drug ... choice, both for treatment ... #Pharmacology #Antibiotics
Achalasia Summary

Epidemiology: 10 cases per 100,000 individuals

Defined by inadequate relaxation of the LES and aperistalsis
Primary or
Neurodegenerative disorders • Infection ... secondary causes leading ... Treatment: Laparoscopic ... Treatment options ... #gastroenterology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome - Overview ... superinfection, drug ... Diagnosis: • Drug ... • Persistently active ... infection/drug