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diagnosis differential hematology intravascular algorithm bruising abnormal anemia bleeding hemolytic prolonged pt arterial avnrt cardiology clots dermatology extravascular hemolysis hemorrhage
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Coagulation (DIC ... Treat primary cause ... #Disseminated # ... #diagnosis #causes
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Disseminated intravascular ... coagulation (DIC ... #Prolonged #Causes
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... hemorrhage • Disseminated ... intravascularcoagulation (DIC ... differential #hematology #coagulation
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Scoring System for Disseminated ... (DIC) Platelet ... aggregation PT, aPTT ... small vessels #DIC ... #Disseminated #
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... endocarditis) - Disseminated ... intravascular coagulation ... MAHA: TTP, HUS, DIC
Visual Guide to AV Nodal Reentrant Tachycardia (AVNRT) - Pathophysiology - Dual AV nodal physiology is
Visual Guide to AV ... Nodal Reentrant ... Pathophysiology - Dual AV ... - In most case ... ECG usually shows
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... HELLP syndrome • Disseminated ... intravascular coagulation ... (DIC) • Anti-coagulation ... Diagnosis #Algorithm #Causes
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
thromboplastin time (PTT ... decompensated DIC ... Diagnosis #Honc #DIC ... LaboratoryFindings #Disseminated ... Intravascular #Coagulation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Rare • Drugs (e.g ... • Vasculitis Coagulation ... Deficiency • Disseminated ... Diagnosis #Algorithm #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): - Disseminated ... intravascular coagulation ... (DIC) - HELLP ... Extravascular #Causes
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