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diagnosis hematology differential intravascular bruising disseminated abnormal algorithm anemia bleeding hemolytic prolonged pt arterial avnrt cardiology clots hemolysis hemorrhage hemostasis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
vs Extravascular ... Causes Intravascular ... coagulation (DIC ... #Extravascular ... #Causes #differential
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Coagulation (DIC ... Treat primary cause ... INR < 2.3 - APTT ... #causes #treatment
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Disseminated intravascular ... coagulation (DIC ... #Prolonged #Causes
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Coagulation (DIC ... aggregation PT, aPTT ... consumption of coagulation ... small vessels #DIC ... #Coagulation #ISTH
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... Causes include : ... intravascularcoagulation (DIC ... differential #hematology #coagulation
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... - Disseminated intravascular ... coagulation (DIC ... MAHA: TTP, HUS, DIC
Visual Guide to AV Nodal Reentrant Tachycardia (AVNRT) - Pathophysiology - Dual AV nodal physiology is
Visual Guide to AV ... Nodal Reentrant ... Pathophysiology - Dual AV ... - In most case ... ECG usually shows
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... • Disseminated intravascular ... coagulation (DIC ... ) • Anti-coagulation ... Diagnosis #Algorithm #Causes
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
thromboplastin time (PTT ... decompensated DIC ... Diagnosis #Honc #DIC ... #Disseminated #Intravascular ... #Coagulation #Labs
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Rare • Drugs (e.g ... • Disseminated Intravascular ... Coagulation ... Diagnosis #Algorithm #Causes
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