7 results
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
pharmacological action ... margin of safety in pharmacology ... the sublingual tablet ... Pharmacokinetics #Comparison ... #Table #Pharmacology
Muscarinic Receptor Agonists and Antagonists 
Muscarinic Receptor Agonists
Methacholine
 • Diagnosis of bronchial airway
Carbachol
 • Glaucorna (topical
Muscarinic Receptor ... symptomatic bradycardia (e.g ... ., AV block) • ... #Medications #Pharmacology ... #Table
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
, acting like benzodiazepines ... Agonist: Mechanism ... uncertain: - Partial agonist ... #medications #pharmacology ... #comparison #table
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
Summary of actions ... some Cholinergic Agonists ... at muscarinic receptors ... #Pharmacology # ... Table #Summary
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... - Pharmacology ... Mechanisms of Action ... Ozempic), or daily tablet ... #Agonists #Pharmacology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... • Heart - ↑ AV ... #actions #pharmacology ... pathophysiology #comparison ... #table
Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
 • Sympathomimetic -
Ideosyncratic reaction ... cessation of dopamine agonists ... (e.g. ... Hyperthermic #Toxidromes #comparison ... #table #diagnosis