6 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... Immunosuppressant Drugs ... cytokine synthesis, e.g ... Immunosuppressant #Drugs ... #Pharmacology #Pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... blood donor • Pathophysiology ... #Transfusion #Reactions ... #hematology #diagnosis ... #comparison #table
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... • Heart - ↑ AV ... adrenergic #receptors #actions ... #pharmacology #pathophysiology ... #comparison #table
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
allergies, and drug ... Classification #Pathophysiology ... Allergy #Diagnosis #Reactions ... #Table
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
hypertension and/or drug ... Constitutional disorders, eg ... reactions - Secondary ... reactions-most ... diagnosis #causes #hematology
PALM RASHES 
Common features and patterns:
1.	Color:
o	Red or erythematous: Common in inflammatory or allergic reactions.
o	Purple or purpuric:
inflammatory or allergic reactions ... suggest vascular or hematologic ... reactions. ... scabies, or allergic reactions ... o Drug Reactions