1634 results
Severe Hydronephrosis on POCUS

Based on this clip, which of the following is most likely abnormal?
Resolution: creatinine
Resolution: creatinine ... Ultrasound #Renal #Nephrology
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 • Nephritic syndrome (Casts)
 • Marked proteinuria (may be
role for IS • Resolution ... GlomeruloNephritis #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
infiltrates) → high resolution ... differential #diagnosis #nephrology
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
intestinal calcium absorption ... and stimulates resorption ... Stimulate calcium reabsorption ... kidney, Stimulates resorption
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
↑ intestinal absorption ... ↑ bone reabsorption ... ↑ tubular reabsorption ... Hypophosphatemia: ↑ bone reabsorption ... ↓↓ tubular reabsorption
Hypercalcemia - Hormones and Pathophysiology  
Calcitriol:
 • Bones: Enhances mineralization
 • GI Tract: ↑ Ca2+
, ↑ PO4- absorption ... , ↑ PO4- reabsorption ... Bones: ↑ Bone resorption ... Bones: ↓ Bone resorption ... , PO4- reabsorption
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext

#Pathophysiology #Mechanism #Nephrology
block glucose reabsorption ... Pathophysiology #Mechanism #Nephrology ... SLGT2 #Inhibitors #Reabsorption
Nephron Reabsorption Sites
 • Proximal Convoluted Tubule
 • Proximal Straight Tubule
 • Thick Ascending Limb
 •
Nephron Reabsorption ... Bladder #Nephron #Reabsorption ... pathophysiology #nephrology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
• Increase Na reabsorption ... • Increase H2O absorption ... KidneyDisease #nephrology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Miscellaneous - Bone Resorption ... - Calcium Reabsorption