19 results
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Renal Effect of ... Synthesis - Renal ... disease -> Decreased renal ... Prostaglandins #Pharmacology
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... cause more alpha-effect ... V2 antidiuretic effect ... 2 mcg/kg/min): renal ... Vasopressors #Inotropes #Pharmacology
Heparin - Unfractionated Heparin (UFH) vs Low-Molecular-Weight Heparin (LMWH)
UFH:
 • Advantages: 
    -
Anticoagulation effect ... monitored - Ok in renal ... anticoagulation effect ... contraindicated in renal ... Unfractionated #pharmacology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Restrictive lung defect ... Abdominal pain (20%) Renal ... erythematosus #signs
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
importance in renal ... production of renal ... unidirectionally to affect ... NSAIDs #Kidney #renal ... #nephrology #pharmacology
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
into the left renal ... - Nutcracker Effect ... : The left renal ... blood in left renal ... Pathophysiology #Signs
Metformin: Biguanide
Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
To avoid this effect ... attention to patients renal ... potential side effect ... #Metformin #Pharmacology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
replication causes direct ... Hypertension - Renal ... Pathophysiology #Diagnosis #Signs
Angiotensin Receptor Blockers 
Recommended Dose Conversions 

Valsartan 
Irbesartan 
Losartan 
Olmesartan 
Telmisartan 
Candesartan 
Azilsartan 
Eprosartan 

A few
irbesartan dose, select ... , CV benefits, renal ... Table #Dosing #Pharmacology
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
produces a ceiling effect ... as its ceiling effect ... margin of safety in pharmacology ... opioid use is resumed ... Comparison #Table #Pharmacology