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diagnosis erythematosus sle differential systemic ana antibodies antinuclear classification criteria dermatology anca antineutrophil antinxp2 antinxp2dm diseases eularacr hematology imdamnsharp joint
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... Polymyositis and dermatomyositis ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... antibodies #diagnosis #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • Systemic lupus ... hemoglobinuria • Antibody-mediated ... Cytomegalovirus • Epstein-Barr ... Differential #Diagnosis #Hematology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... A Antinuclear Antibody ... Arthritis R Renal ... sle #systemic #lupus ... erythematosus #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
- SEROSITIS - RENAL ... - Anti-dsDNA antibody ... the presence of antibody ... Antiphospholipid antibody ... #Diagnosis #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
hemolysis • Renal ... Antiphospholipid antibody ... domain: Anti-dsDNA antibody ... , Anti-Sm antibody ... Erythematosus #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Seborrhea • Dermatomyositis ... Heliotrope • Dermatomyositis ... Antiphospholipid-antibody ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
or Anti-NucIear Antibody ... , Drug-induced Lupus ... , Polymyositis/Dermatomyositis ... , Drug-Induced Lupus ... ANA #patterns #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Abdominal pain (20%) Renal ... Thrombocytopenia #Lupus ... erythematosus #signs ... symptoms #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Erythematosus #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... such as systemic lupus ... purpura: strong sign ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
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