43 results
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
Colchicine Toxicity ... Rhabdomyolysis • Renal ... failure • Metabolic ... #Colchicine #Toxicity ... Toxicology #Symptoms #Signs
Flapping tremors of Asterixis

DDx
- Decompensated cirrhosis or acute liver failure.
- Renal failure /azotemia.
- Respiratory failure with
or acute liver failure ... - Renal failure ... - Respiratory failure ... carbon dioxide toxicity
Thyroid Eye Signs 
Lid Signs
    Dalrymple’s Sign: Lid Retraction.
    Von
(Figure 1) ... (Figure 1) ... (Figure 2) ... (Figure 3) ... #EPONYMS #ENDOCRINOLOGY
Breast Discharge - Differential Diagnosis Algorithm
High Prolactin + Normal TSH
 • Microprolactinoma
 • Steroid Hormone Intake
Intake • Chronic Renal ... Failure • Stress ... Production • Renal ... Cancer or Failure ... Diagnosis #Algorithm #Endocrinology
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
Aspirin - salicylate toxicity ... ketoacidosis Renal ... failure - underexcretion ... acids in advanced renal ... failure Ketoacidosis
Hyperkalemia - Differential Diagnosis - Impaired Excretion vs Redistribution

Impaired Urinary Excretion 
 - Renal failure
 -
Excretion - Renal ... failure - Hypoaldosteronism ... Succinylcholine - Digoxin toxicity
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... absent in severe toxicity ... Progressive multi-organ failure ... coagulopathy, renal ... failure) Hepatotoxicity
Clinical Features of Infective Endocarditis

General 
 - Malaise 
 - Clubbing 

Cardiac 
 - Murmurs
Murmurs - Cardiac failure ... Mycotic aneurysm Renal ... Endocarditis #Symptoms #Signs
Hyperthyroidism – symptoms and signs. 

Symptoms:

Weight loss, Increased appetite, Irritability/behaviour change, Restlessness, Malaise, Stiffness, Muscle weakness,
– symptoms and signs ... ), Sweating Signs ... hypertension, Cardiac failure ... Hyperthyroidism #Symptoms #Signs ... #Diagnosis #Endocrinology
Cardiorenal Syndrome (CRS) Types
 • Type 1 - Acute CRS: Alteration of renal perfusion is the
Alteration of renal ... congestive heart failure ... - Chronic CRS: Renal ... toxicity and VAD ... induced renal effects