11 results
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Symptoms: B-symptoms, bruising ... anemia, ↑ MCV, ↑/↓ platelets ... , persistent WBC ... #WBC #Leukemoid
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... , CD3 Chronic ... bcr-able (+) ↑ WBC ... #hematology #Markers ... #Differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Disorders - Differential ... decreased PLT count: CBC ... disease), HBsAg/anti-HBc ... #Disorders #Differential ... Causes #Workup #hematology
A cirrhosis tweetorial all about the platelet

Aims:
- Identify cirrhosis based on blood tests- 
- Understand why
all about the platelet ... Understand why platelets ... #Cirrhosis #CBC ... #Tweetorial #Hepatology ... #Pathophysiology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Pancytopenia - Differential ... < 1800/uL, • platelet ... Initial Workup: CBC ... #Pancytopenia #Differential ... Diagnosis #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Artifact (redo CBC ... • Rheumatic disorders ... Thrombocytosis #Differential ... Algorithm #Causes #Hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Even with normal WBC ... relative to both WBC ... 21% had normal WBC ... diagnosis #neutrophil #WBC ... #CBC #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... with or without platelet ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... membrane disorder
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Diagnosis: On the CBC ... , RBCs & WBCs are ... abnormality is platelet ... widely varying platelet ... hemoproliferative disorder
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hematological malignancy arising ... • Autoimmune disorders ... - Low Hb and platelets ... - WBC may be ... Immunohistochemical studies (to differentiate