174 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... to 8 years Clinical ... history of recurrent infections ... community-acquired infections ... Malignancies • Chronic infections
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... TPO, TPO-RA • Infections ... : Chronic infections ... bacterial and viral infections
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
Diagnosis, causes and management ... cryoglobulinemia vasculitis Clinical ... related to HBV infection ... with refractory disease ... Cryoglobulinemia #Vasculitis #Rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... differential #diagnosis #hematology
Medial Approach Knee Intra-articular Corticosteroid Injection 

Landmark 1/3 to 1/2 way from top of patella. Find
Corticosteroid Injection ... Corticosteroid #Injection ... #clinical #video ... #orthopedics #sports ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Acquired HLH: • Infections ... , Infection under ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
Characteristic clinical ... manifestations of Down syndrome ... • Brushfield spots ... susceptibility to infections ... #Downs #Syndrome
Campylobacter
Clinical 
 • Fever 
 • Abdominal pain 
 • Diarrhea (bloody stools) 
 • Vomiting
Campylobacter Clinical ... Guillain-Barré syndrome ... Management ... • Supportive (infection ... Antibiotics for severe disease
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Adjuvant therapies in critical ... diseases - Severe ... respiratory distress syndrome ... InfectiousDiseases #Infections ... #Pharmacology #Management
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
associated with infection ... (90%), Fungal infections ... • Dental infections ... • Dental infections ... vision or black spots