35 results
hematology differential oncology treatment algorithm causes hemolysis skin anticoagulation chronic cll disease eosinophilia eosinophils hasbled hemolytic hypereosinophilia intravascular leukemia lymphocytic
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Clinically ... Relevant HES Variants ... disorders • Diagnosis ... #HES #Hematology ... #management #algorithm
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... #hematology #hemolysis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #hematology #oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... • TTP/HUS • ... Algorithm #Causes #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Purpura (TTP) Diagnosis ... soon as TTP is diagnosed ... PLEX and RTX • Short-term ... Thrombocytopenic #Purpura #management ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... (HUS) • Other ... #hematology #anemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... #hematology #rheumatology ... #nonpalpable #dermatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... - MAHA: TTP, HUS ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... Constitutional Syndromes ... #oncology #hematology ... #diagnosis #management
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
calculators - HAS-BLED ... studies suggest net clinical ... Bleeding #Risk #Scores ... Anticoagulation #Factors #Hematology ... #Diagnosis
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