37 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Rebound effect from treatment ... Malignancy: Metastatic cancer ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Differential Diaqnoses ... hemopathies, solid cancers ... #diagnosis #management ... #treatment #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... thrombocythemia), Autoimmune disease ... adsorption onto cancer ... #treatment #hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... Treatment: • ... Hydroxychloroquine *Short ... #SLE #Summary #diagnosis ... #rheumatology #
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Lymphoma or other cancers ... gastric and breast cancer ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
with or without treatment ... , but without treatment ... reddish brown spots ... Syphilis #Rash #Diagnosis ... #Clinical #Photo
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... ) Differential Diagnosis ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Clinical Triad ... - Recurrent disease ... arterioles - Treatment ... SusacSyndrome #Triad #Diagnosis ... #Management #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... permeability Diagnosis ... CNS #neurology #rheumatology