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diagnosis management hematology differential disease comparison gout lupus oncology syndrome activetb algorithm approach causes cll druginduced hemeonc joint latenttb leukemia
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... inflammatory arthritis ... Chronic CPP Crystal ... Inflammatory Arthritis ... Gout #Comparison #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... Chronic CPP Crystal ... Resembles RA • Chronic ... Acute Pseudogout: Treatment ... Deposition #Disease #Rheumatology
Approach to Gout Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals Treatment: • Weight loss, diet, d/c culprit
Diagnosis: r/o septic arthritis ... birefringent crystals Treatment ... Colchicine: Acute and chronic ... treatment • Chronic ... #ULT #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Polycythemia Vera • Chronic ... : • Acute or Chronic ... effect following treatment ... following EtOH induced thrombocytopenia ... Algorithm #Causes #Hematology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
maculopapular rash, arthritis ... low ferritin, arthritis ... and chronic synovitis ... (40%) Treatment ... Disease #AOSD #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
• Inflammatory arthritis ... Noninflammatory arthritis ... : • Acute or chronic ... Joint #Pain #MSK #rheumatology ... #approach #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... • Infections: Chronic
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Symptoms of anemia or thrombocytopenia ... with anemia or thrombocytopenia ... uw_IMresidency #CLL #Chronic ... Leukemia #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
transfusion • Thrombocytopenia ... protein C and S Pathophysiology ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced Thrombocytopenia ... ♀, ↑Age, ESRD Pathophysiology ... consumption → thrombocytopenia ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
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