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diagnosis cryoglobulinemic management classification dermatology differential hematology cell cryoglobulins dermatologic gpa granulomatosis involvement monoclonal nephrology nonpalpable oncology palpable plasmacytoma polyangiitis
Treatment of Non-hepatitis C virus Cryoglobulinemia Vasculitis - French Vasculitis Study Group MONOCLONAL CRYOGLOBULINEMIA (TYPE 1) IgM
Treatment of Non-hepatitis ... lenalinomide MIXED ... TerrierBen #NonHCV ... #Rheumatology # ... Monoclonal #Mixed
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
Non-HCV infectious mixed ... neuropathy Treatment ... TerrierBen #NonHCV ... #Vasculitis #Rheumatology ... #Mixed #Cryoglobulinemic
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Vasculitis 1 ... 3 types 2) Vasculitis ... Hyperviscosity syndrome MIXED ... #Vasculitis #Diagnosis ... #Rheumatology #
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
involvement in 35% of mixed ... cryoglobulinemia ... vasculitis Associated ... #Vasculitis #Management ... #Rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
, in Mixed Cryoglobulinemia ... seen with the mixed ... Etiology - Mixed ... II and III are Mixed ... classification #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Ig A vasculitis ... /HSP • Cryoglobulinemia ... (MIXED) • ANCA ... Differential #Diagnosis #hematology ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... ANCA +MPO) • Cryoglobulinemic ... Complement (Low levels mixed ... cryoglobulinemia ... differential #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Pauci-immune vasculitis ... Henoch-Schönlein purpura • Mixed ... cryoglobulinemia ... Granulomatous vasculitis ... rash #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... : • 7%, Cryoglobulinemia ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
marrow, e.g., ribs ... the periphery, creating ... • Vertebrae • Ribs ... Bone marrow Treatment ... Diagnosis #Workup #Hematology
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