6 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... workup, including BM ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... #management #treatment ... #summary #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... Coxsackie, CMV, EBV ... #management #treatment ... #rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
Lymphocytopenia DIAGNOSTIC ... CRITERIA FOR ICL ... EBV. CMV. ... #diagnosis #hematology ... #Differential #
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... Hodgkins #lymphoma #diagnosis
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Neutropenia - Differential ... Diagnosis Neonate ... hypertension and/or drug treatment ... replacing the BM ... #hematology