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algorithm hepatology liver causes acute lfts oncology rheumatology transaminitis adultonset anemia aplastic classification dili disease druginduced effusions hemophagocytic hepatocellular hlh
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... normal - Infection (EBV ... #hepatology #LFTs ... transaminitis #differential ... #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... Diagnosis Hepatocellular ... C, A, E, B, D, EBV ... #Differential #
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Differential Diagnosis ... • Infections: Hepatitis ... A/B/C/D/E, EBV, ... Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... Diagnosis Baseline ... ANCA, ANA, Anti-GBM ... cryoglobulins, hepatitis ... Acute #Kidney #Injury
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... HBV, HCV, HEV, EBV ... #Diagnosis #Algorithm ... #hepatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Coxsackie, CMV, EBV ... hepatomegaly, hepatitis ... #management #treatment ... #rheumatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... HBV, HCV, HEV, EBV ... #hepatitis #differential ... #hepatology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Knee Effusions - Differential ... Diagnosis Framework ... bearing after injury ... HSV, Varicella, EBV ... Parvovirus - Hepatitis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... Aplastic Anemia: - Hepatitis ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Unknown cause Treatment ... of emergency, ICU ... #management #treatment
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