13 results
Multiple Uses for Tranexamic Acid (TXA) - Evidence Based Indications and Dosing

Trauma < 3 hrs •
Tranexamic Acid (TXA ... and Dosing Trauma ... Thinking MTP YES ICH ... Indications #management #EBM ... #trauma
CRASH-3: TXA for ICH? #TXA #managment #EBM #CRASH3 #trauma
CRASH-3: TXA for ... ICH? ... #TXA #managment ... #EBM #CRASH3 #trauma
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Urine Common Uses: Trauma ... , Post-partum, ICH ... disturbances #TXA ... #Pharmacology #hematology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Findings: Coombs positive ... Mycoplasma, HIV, EBV ... Findings: Coombs Positive ... Hemolytic #Anemia #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... workup, including BM ... • Nonmalignant hematologic ... infarction, Severe trauma ... Diagnosis #Algorithm #hematology
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
HAV, HCV, HEV, EBV ... Congenital: HELLP • Trauma ... Diagnosis #causes #hepatology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
- NEJM 1999 - ICU ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
anti-HBc (rituximab tx ... or if a primary hematologic ... When do you do a BM ... Causes #Workup #hematology
Reactive or "Atypical" Lymphocytosis
Infection
 • Viral: EBV, CMV, HIV, Herpes viruses, Influenza, Varicella, HTLV-I
 • Bacterial:
Infection • Viral: EBV ... Hyperthyroidism • Trauma ... differential #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
dehydrogenase • Positive ... - Mycoplasma, EBV ... hemolytic #anemia #hematology