11 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... anemia 4% - Myositis ... #Lupus #Erythematosus ... #rheumatology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
and Arthritis in Pediatrics ... Patient - Differential ... Suggestive of: Rheum Fever ... Suggestive of systemic ... gabrieltalledop #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... permanent alopecia Differential ... to: Arthritis, Fever ... Thrombosis highest risk
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
drug-induced SLE High risk ... to low (0.1-1%) Risk ... Terbinafin Low risk ... very low (<0.1%) risk ... #pharmacology #risk
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... 9) Unexplained fever ... including in children (pediatric ... diagnosis #sle #clues #system ... #erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... ischemia - Skin: erythematous ... Coronary arteries - Fever ... lupus erythematosus ... Vasculitis: • Fevers
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Infections in HIV - Differential ... papules, pustules, erythematous ... Pneumonia: • Risk ... Infections #HIV #AIDS ... #pulmonary #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis: • Fevers ... ischemia • Skin: Erythematous ... Conjunctivitis, mucositis ... #Diagnosis #Rheumatology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
infection (IFI) in hematologic ... useful in high risk ... BAL GM does not differentiate ... post-2010 almost never ... HSCT; with GIT mucositis
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
disease Malignancy Risk ... and increased risk ... dermatomyositis) Malignancy Risk ... and increased risk ... and increased risk