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rheumatology ana antibodies lupus management systemic algorithm clinical diseases anca antibody antineutrophil arthropathies arthropathy autoantibodies causes classification disorders flair gravis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Syndrome (SS), Polymyositis ... Kumfer @AnnKumfer #Antinuclear ... #rheumatology #diagnosis ... #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... Syndrome (SS), Polymyositis ... #rheumatology #diagnosis ... #differential
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... activity Anti-Ro ... #Erythematosus ... #SLE #Summary #diagnosis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
40% Target: SS-A/Ro ... is clinically suspected ... overlap syndromes ... #erythematosus ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Clinical Features
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... Erythematosus ( ... SLE), should have ... Joint #Disorders #msk
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... erythematosus ... in drug-induced SLE ... cases • Sjögren syndrome ... Anti-Ro/SSA
Patterns of Diseases on MRI FLAIR - Differential Diagnosis ADEM, Adreno-leukodystrophy, CADASIL, CNS, Lymphoma, High-Grade Glioma, HIV
Patterns of Diseases ... on MRI FLAIR - Differential ... Diagnosis ADEM ... Disease, Susac Syndrome ... #clinical
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Diagnosis Algorithm ... Arthritis • Systemic Lupus ... Erythematosus ... Sicca) Syndrome ... Inflammatory #JointPain #MSK
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
such as systemic lupus ... erythematosus, ... - (C-ANCA) pattern ... - (P-ANCA) pattern ... vasculitis, and SLE
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