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rheumatology lupus management systemic algorithm ana arthritis criteria workup antibodies approach arthropathies arthropathy autoantibodies causes classification clinical disease disorders eularacr
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... Erythematosus ( ... SLE), should have ... #Disorders #msk ... #Differential #
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... 40% Target: SS-A/Ro ... is clinically suspected ... #erythematosus ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... permanent alopecia Differential ... Arthritis: • Joint ... arthropathy • 90% joints
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Pain - Differential ... Diagnosis Algorithm ... Arthritis • Systemic Lupus ... Erythematosus ... Inflammatory #JointPain #MSK
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... INVOLVING 2 OR MORE JOINTS ... SEROSITIS - RENAL - NEUROLOGIC ... #Lupus #Erythematosus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... Kumfer @AnnKumfer #Antinuclear ... #rheumatology #diagnosis ... #differential
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Clinical Domains ... in at least 2 joints ... • Neurologic ... Classification #Criteria #SLE ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #Joint #Pain #MSK ... approach #workup #differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
• Systemic lupus ... erythematosus ( ... SLE) - Antinuclear ... (to support a diagnosis ... ANA and RF (if clinical
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Antibodies: Anti-Ro ... ab • RF • Antinuclear ... salivary ducts Clinical ... phenomenon (16%) MSK
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