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management hematology disease oncology pathophysiology rheumatology algorithm deficiency erythematosus fever infections infectiousdiseases lupus neurology pulmonary refeeding sle systemic agglutinin arteritis
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
• Vitamin E - Haemolytic ... Wernicke-Korsakoff syndrome ... Vitamins #Deficiency #differential ... #diagnosis #signs ... #symptoms #nutrition
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
diarrhoea, Short bowel syndrome ... dental fixatives, Treatment ... Haematological: Anaemia ... Copper #Deficiency #diagnosis ... #symptoms #nutrition
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diagnosis Congenital ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis ... Nutritional
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... • Tumor lysis syndrome ... associated with any symptoms ... #diagnosis #Laboratory
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... of anemia include ... Diagnosis: • hemolytic ... anemia • Cold ... younger pts) Differential
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
- Little or no nutritional ... -DPG -> - hemolysis ... - anemia ... #diagnosis #pathophysiology ... #symptoms #signs
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
overload) Other Symptoms ... • Seizures • Hemolysis ... hyperparathyroidism Treatment ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
suspected: • Signs ... and symptoms of ... Iron-deficiency anemia ... unresponsive to treatment ... microscopic colitis Differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... ) Blood (75%): Anemia ... normochromic nomocytic or haemolytic ... erythematosus #signs ... #symptoms #diagnosis
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