48 results
Causes of SVC Syndrome - Differential Diagnosis Framework
 • Benign (15-40%): Thrombosis (aka catheter-associated), Goiter, Fibrosing
Malignant (60-85%): SCLC ... , NSCLC, NHL, Germ
Small Cell Lung Cancer (SCLC) Staging
SCLC has 2 stages: 'Limited' or 'Extensive'
Limited = disease fitting into
Cell Lung Cancer (SCLC ... ) Staging SCLC has ... #Lung #Cancer #SCLC
The PET better demonstrates the extent of the lymphnode metastases in this patient.
Final diagnosis: small cell
Window #Fullness #SCLC
Here another case. On the PA-film a mass is seen that fills the aortopulmonary window. Final
Window #Fullness #SCLC
Subacute Cutaneous Lupus erythematosus (SCLE): Erythematous, warm, plaques in light exposed distribution (also on patient's neck),
erythematosus (SCLE ... Erythematosus (SCLE ... Erythematosus #SCLE
Causes of Superior Vena Cava (SVC) Syndrome 
Malignant Causes (2/3 of cases)
 - 95%
Cancer - NSCLC ... common) - SCLC
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
ALL, Burkitt, SCLC
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anti-centromere, Scl
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
syndrome Anti-Scl