689 results
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
retinal exudates) - SLE ... • Interstitial lung ... nodules - RA, SLE ... • Shrinking lung ... syndrome - SLE
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... Associated with SCLE ... Associated with SLE-SSc-AlM ... patients with typical SLE
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... syndrome Anti-Scl ... Diffuse) Anti-Sm - SLE
Cutaneous Lupus Erythematosus
 • Acute Cutaneous Lupus (ACLE)
 • Neutrophilic Dermatoses 
 • Vascular Lesions
 •
Cutaneous Lupus (ACLE ... Cutaneous Lupus (SCLE ... Cutaneous Lupus (ICLE ... Cutaneous Lupus (CCLE
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... Erythematosus #SLE
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SLE ... pattern: - SjS, SLE ... Speckled: - SLE ... conditions, SjS, SLE ... Golgi/polar: - SLE
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... is rare in DIL, SCLE-DIL ... Erythematosus (SLE ... are evocative of SLE ... management of SLE
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... erythematosus (SCLE ... : Drug induced SLE ... SSA can rule in SLE ... papillomavirus #SLE
Causes of Diffuse Lung Disease. 
Collagen vascular 
 - Scleroderma 
 - Rheumatoid arthritis 
 -
Causes of Diffuse Lung ... Dermatomyositis - SLE ... Causes #Diffuse #Lung
Approach to a Positive (+) Rheumatoid Factor (RF)
(+) RF does not always = RA
Rheumatic disorders:
 •
arthritis • SLE ... disorders of Liver & Lung