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Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD EMPA-REG OUTCOME - Empagliflozin lowered CV events
Selected Clinical ... Trials of SGLT2 ... ASCVD; signal for SGLT2i ... risk; signal for SGLT2i ... mcclaffertyMD #SGLT2
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
drugs Other than SGLT2i ... metformin in T2D and CKD ... receptor agonist SGLT2i ... , #KDIGO2020 #CKD ... Management in CKD
Diabetes Medications Summary Table Insulin Lifestyle modifications Metformin Sulfonylureas GLP-1 receptor agonists - ↓ major adverse CV events TZDs DPP-4 inhibitors SGLT2 inhibitors -
-4 inhibitors SGLT2 ... Improved outcomes in CKD
Complications of CKD - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
Complications of CKD ... >30 mL/min) of CKD ... derangements are not clinically ... disturbances manifest clinically ... in CKD stages 4
Metabolic Acidosis with Anion Gap - KILU Mnemonic K - Ketoacidosis • DKA - With normal glucose, ask if
normal glucose, ask ... if on SGLT2 inhibitor ... ketoacidosis in SGLT2 ... inhibitors and SGLT2
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
AKI) What to ask ... - Hx of AKI/CKD ... 21% - AKI on CKD
#VisualAbstract for #Lancet trial #CANVASR #SGLT2i #Canagliflozin "Canagliflozin and renal outcomes in type 2 diabetes: results from
trial #CANVASR #SGLT2i ... Program randomised clinical
Chronic Kidney Disease (CKD): Individualize BP-lowering therapy and treatment targets in people with frailty, high risk of
Kidney Disease (CKD ... progression of CKD ... include RASiand SGLT2i ... heart failure, SGLT2i ... both RASI and SGLT2i
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Normal CK ... Weakness, Incr CK ... therapy), Normal CK ... Erythematosus #SLE #MSK
Choledochodudodenal Fistula on Endoscopy Patient admitted with cholangitis, dilated CHD and IHBDs, remote cholecystectomy. I found
cholangitis, dilated CHD ... resulting in partial CBD ... gastroenterology #clinical
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