9 results
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Acetazolamide, others SGLT2 ... Tolvaptan #Diuretics ... #Medications #Pharmacology ... summary #table #nephrology
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Metformin + SGLT2 ... dapagliflozin) Dpp4 + SGLT2 ... Combination #Tablets #Oral ... #DM2 #Pharmacology
#visualabstract #sglt2i #nephrology
#visualabstract ... #sglt2i #nephrology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... - Pharmacology ... Action: Inhibits SGLT2 ... leading to osmotic diuresis ... EricsMedicalLectures/featured #SGLT2
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... are similar to diuretics ... /ambcarerx #SGLT2 ... #Inhibitors #Pharmacology
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
a.k.a. osmotic diuresis ... : Conventional diuretics ... diabetes mellitus, SGLT2 ... Diagnosis #Causes #nephrology
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
Oral Hypoglycemics ... Prandase) • SGLT ... @AmyChung #Oral ... Diabetes #Management #pharmacology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
Rybelsus (oral semaglutide ... ) - First Oral GLP ... first (& only) oral ... when compared to SGLT2 ... semaglutide #Diabetes #Pharmacology
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
ARNI, BBs, Loop diuretics ... , MRA, SGLT2i, Nitrate ... HFrEF #management #pharmacology