5795 results
Tweetorial - Stevens Johnson Syndrome (SJS)

By Dr. Steven Chen @DrStevenTChen

#StevensJohnsonSyndrome #SJS #Dermatology #Diagnosis #Tweetorial #Pathphysiology
Johnson Syndrome (SJS ... StevensJohnsonSyndrome #SJS ... #Dermatology #Diagnosis
Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN) and Overlap

 SJS-TEN overlap and TEN - Surface Epidermal
Stevens-Johnson syndrome (SJS ... and Overlap SJS-TEN ... Distinguishing Features #SJS ... Necrolysis #Comparison #Diagnosis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SjS ... Raynaud phenomenon, SjS ... PBC/SSc OS, PBC/SjS ... polar: - SLE, SjS ... #differential #diagnosis
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
PBC/SSc OS, PBC/SjS ... Speckled: • SLE, SjS ... Neurologic conditions, SjS ... polar: • SLE, SjS ... #differential #diagnosis
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
Fever and Rash - Diagnostic ... (Strep/Staph), SJS ... or Pustular: SJS ... Rash #Febrile #Diagnosis
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
to Weeks (Rash, SJS ... Classification #Allergy #Diagnosis
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
- Differential Diagnosis ... Noninfectious: SJS ... #Differential #Diagnosis
Causes of Pharyngitis - Differential Diagnosis
Infectious:
 • Bacterial: Group A Strep, Group B and C Strep,
- Differential Diagnosis ... stomatitis Drugs: SJS ... #Differential #Diagnosis
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
differentiating between the diagnosis ... Video #Clinical #SJS
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
- Differential Diagnosis ... Framework Diagnosis ... effect/reaction (ie SJS ... #Differential #Diagnosis